Dr. S. KAMARAJ

ASSISTANT PROFESSOR
Department of Biotechnology
Email :kamaraj07@periyaruniversity.ac.in
Education
Course Institution
B.SC Periyar University ( 2003 )
M.SC Bharathidasan University ( 2005 )
M.PHIL University of Madras ( 2006 )
PH.D University of Madras ( 2009 )
Professional Experience
Field Company / Institution Designation
Research Dept. of Molecular Biology, Umeå University, Sweden Postdoc ( 2009 - 2012 )
Research Dept. of Medical Biochemistry, Umeå University, Sweden Postdoc ( 2013 - 2015 )
Teaching Periyar University, PG Extension Centre Assistant Professor ( 2017 - Present )
Specializations
Molecular Oncology
DNA Damage checkpoint activation and repair
Drug Discovery
Awards
S.No Award Title Date of Award Level Sponsor Sponsor Address
112009-03-21InternationalAFRR-2009C.S.M. Medical University and Era’s Lucknow Medical College, Lucknow, India.
212008-04-01NationalICMRIndian Council of Medical Research, New Delhi, Govt. of India.
312019-09-30InternationalTANSCSTUniversity of Missouri, USA and Crescent Institute of Science and Technology,Chennai, India
Total No. of Ph.D’s. and M.Phil’s. Produced
Degree Awarded Submited On-roll
M.Phil 11 0 0
Ph.D 11 0 0
Research Project
S.No Title Status Funding Agency
1ELUCIDATION OF MOLECULAR MECHANISMS UNDERLYING THE ANTICANCER PROPERTY OF NEOANDROGRAPHOLIDE IN NEUROBLASTOMA CELLS UGC-BSR
2STUDY ON THE EFFECTS OF DIVERSE SEASONAL AND GEOGRAPHICAL VARIATIONS ON MALARIA VECTORS AND STUDY ON THE ASSOCIATION OF GUT MICROBIOME WITH MALARIAL VECTORS STATUS AND EFFECTS OF SEASONAL AND GEOGRAPHICAL VARIATIONS ON THE MICROBIOME OF THE NORTHEAST INDIA AND SOUTH INDIAN ANOPHELES MOSQUITOES Sanctioned ICMR
3 INCULPATE OF AEDES MOSQUITOES AS VECTOR OF ZIKA VIRUS AND INVESTIGATE IN LIMITED DISTRICT OF TAMILNADU (SALEM, DHARMAPURI, AND KRISHNAGIRI) Sanctioned TNSCST
Publications

  1. Kamaraj S, Vinodhkumar R, Anandakumar P, Jagan S, Ramakrishnan G, Devaki T, The effects of quercetin on antioxidant status and tumor markers in the lung and serum of mice treated with benzo(a)pyrene, Biological and Pharmaceutical Bulletin, 30(12), 2268-73, 2007, Pharmaceutical Society of Japan(1.8200)

  2. Anandakumar P, Kamaraj S, Jagan S, Ramakrishnan G, Vinodhkumar R, Devaki T, Capsaicin modulates pulmonary antioxidant defense system during benzo(a)pyrene- induced lung cancer in Swiss albino mice, Phytotherapy Research, 22(4), 529-33, 2008, John Wiley & Sons(3.0900)

  3. Anandakumar P, Kamaraj S, Jagan S, Ramakrishnan G, Vinodhkumar R, Devaki T, Stabilization of pulmonary mitochondrial enzyme system by capsaicin during benzo(a)pyrene induced experimental lung cancer, Biomedicine & Pharmacotherapy, 62(6), 390-4, 2008, Elsevier(3.4570)

  4. Jagan S, Ramakrishnan G, Anandakumar P, Kamaraj S, Devaki T, Antiproliferative potential of gallic acid against diethylnitrosamine-induced rat hepatocellular carcinoma, Molecular and Cellular Biochemistry, 319(1), 51-9, 2008, Springer Science+Business Media(2.0570)

  5. Anandakumar P, Jagan S, Kamaraj S, Ramakrishnan G, Titto AA, Devaki T, Beneficial influence of capsaicin on lipid peroxidation, membrane-bound enzymes and glycoprotein profile during experimental lung carcinogenesis., Journal of Pharmacy and Pharmacology, 60(6), 803-8, 2008, Wiley-Blackwell(2.4050)

  6. Ramakrishnan G, Elinos-Báez CM, Jagan S, Augustine TA, Kamaraj S, Anandakumar P, Devaki T, Silymarin downregulates COX-2 expression and attenuates hyperlipidemia during NDEA-induced rat hepatocellular carcinoma., Molecular and Cellular Biochemistry, 313(1), 53-61, 2008, Springer Science+Business Media(2.0570)

  7. kamaraj S, Ramakrishnan G, Anandakumar P, Jagan S, Devaki T, Antioxidant and anticancer efficacy of hesperidin in benzo (a) pyrene induced lung carcinogenesis in mice, Investigational New Drugs, 27(3), 214-222, 2009, Springer US(3.5200)

  8. Ramakrishnan G, Jagan S, Kamaraj S, Anandakumar P, Devaki T, Silymarin attenuated mast cell recruitment thereby decreased the expressions of matrix metalloproteinases-2 and 9 in rat liver carcinogenesis. , Investigational New Drugs, 27(3), 233-40, 2009, Springer(3.5020)

  9. Anandakumar P, Kamaraj S, Jagan S, Ramakrishnan G, Devaki T, Effect of capsaicin on glucose metabolism studied in experimental lung carcinogenesis, Natural Product Research, 23(8), 763-74, 2009, Taylor & Francis(1.8280)

  10. Ramakrishnan G, Lo Muzio L, Elinos-Báez CM, Jagan S, Augustine TA, Kamaraj S, Anandakumar P, Devaki T., Silymarin inhibited proliferation and induced apoptosis in hepatic cancer cells., Cell Proliferation, 42(2), 229-40, 2009, John Wiley & Sons Ltd(4.9360)

  11. Anandakumar P, Kamaraj S, Jagan S, Ramakrishnan G, Devaki T, Lysosomal abnormalities during benzo(a)pyrene-induced experimental lung carcinogenesis-defensive role of capsaicin., Fundamental & Clinical Pharmacology, 23(1), 97-103, 2009, John Wiley & Sons Ltd(2.3490)

  12. Anandakumar P, Kamaraj S, Jagan S, Ramakrishnan G, Naveenkumar C, Asokkumar S, Devaki T, Capsaicin alleviates the imbalance in xenobiotic metabolizing enzymes and tumor markers during experimental lung tumorigenesis, Molecular and Cellular Biochemistry, 331(1), 135-43, 2009, Springer Science+Business Media(2.0570)

  13. Anandakumar P, Kamaraj S, Ramakrishnan G, Jagan S, Devaki T, Chemopreventive task of capsaicin against benzo(a)pyrene-induced lung cancer in Swiss albino mice., Basic & Clinical Pharmacology & Toxicology, 104(5), 360-5, 2009, Wiley (2.6590)

  14. Anandakumar P, Jagan S, Kamaraj S, Ramakrishnan G, Clara JB, Pathitha D, Kavitha T, Devaki T, Ameliorating effect of capsaicin on alterations in lipid metabolism during mice lung carcinoma., Archives of Pharmacal Research, 32(2), 229-34, 2009, Springer Science+Business Media(2.3240)

  15. Kamaraj S, Anandakumar P, Jagan S, Ramakrishnan G, Devaki T, Modulatory effect of hesperidin on benzo(a)pyrene induced experimental lung carcinogenesis with reference to COX-2, MMP-2 and MMP-9., European Journal of Pharmacology, 15(1), 320-7, 2010, Elsevier(2.8960)

  16. Martinsson T, Eriksson T, Abrahamsson J, Caren H, Hansson M, Kogner P, Kamaraj S, Schönherr C, Weinmar J, Ruuth K, Palmer RH, Hallberg B, . Appearance of the novel activating F1174S ALK mutation in neuroblastoma correlates with aggressive tumor progression and unresponsiveness to therapy., Cancer Research, 71(1), 98-105, 2011, American Association for Cancer Research (AACR)(9.1300)

  17. Schönherr C, Ruuth K, Eriksson T, Yamazaki Y, Ottmann C, Combaret V, Vigny M, Kamaraj S, Palmer RH, Hallberg B, The neuroblastoma ALK(I1250T) mutation is a kinase-dead RTK in vitro and in vivo, Translational Oncology, 4(4), 258-265, 2011, Elsevier(3.0710)

  18. Kamaraj S, Anandakumar P, Jagan S, Ramakrishnan G, Devaki T, Hesperidin attenuates mitochondrial dysfunction during benzo(a)pyrene-induced lung carcinogenesis in mice, Fundamental & Clinical Pharmacology, 25(1), 91-8, 2011, Wiley (2.3490)

  19. Schönherr C, Ruuth K, Kamaraj S, Wang CL, Yang HL, Combaret V, Djos A, Martinsson T, Christensen JG, Palmer RH, Hallberg B, Anaplastic Lymphoma Kinase (ALK) regulates initiation of transcription of MYCN in neuroblastoma cells , Oncogene , 31(50), 5193-5200, 2012, Nature Publishing Group (6.8500)

  20. Anandakumar P, Kamaraj S, Jagan S, Ramakrishnan G, Asokkumar S, Naveenkumar C, Raghunandhakumar S, Devaki T, Capsaicin inhibits benzo(a)pyrene-induced lung carcinogenesis in an in vivo mouse model., Inflammation Research , 61(11), 1169-75, 2012, Springer Science+Business Media(2.1430)

  21. Asokkumar S, Naveenkumar C, Raghunandhakumar S, Kamaraj S, Anandakumar P, Jagan S, Devaki T, Antiproliferative and antioxidant potential of beta-ionone against benzo(a)pyrene- induced lung carcinogenesis in Swiss albino mice, Molecular and Cellular Biochemistry, 363(1), 335-45, 2012, Springer Science+Business Media(2.0570)

  22. Jayakumar S, Madankumar A, Asokkumar S, Raghunandhakumar S, Gokula dhas K, Kamaraj S, Divya MG, Devaki T, Potential preventive effect of carvacrol against diethylnitrosamine-induced hepatocellular carcinoma in rats, Molecular and Cellular Biochemistry, 360(1), 51-60, 2012, Springer Science+Business Media(2.0570)

  23. Naveenkumar C, Asokkumar S, Raghunandhakumar S, Jagan S, Anandakumar P, Augustine TA, Kamaraj S, Devaki T., Potent antitumor and antineoplastic efficacy of baicalein on benzo(a)pyrene-induced experimental pulmonary tumorigenesis., Fundamental & Clinical Pharmacology, 26(2), 259-70, 2012, Wiley(2.3490)

  24. Sattu kamaraj, Hochgräfe F, Wu J, Umapathy G, Schönherr C, Ruuth K, Chand D, Witek B, Fuchs J, Li PK, Hugosson F, Daly RJ, Palmer RH, Hallberg B, Phosphoproteomic analysis of anaplastic lymphoma kinase (ALK) downstream signaling pathways identifies signal transducer and activator of transcription 3 as a functional target of activated ALK in neuroblastoma cells , FEBS Journal , 280(21), 5269-5282, 2013, Wiley (4.5300)

  25. Anandakumar P, Kamaraj S, Jagan S, Ramakrishnan G, Devaki T, Capsaicin provokes apoptosis and restricts benzo(a)pyrene induced lung tumorigenesis in Swiss albino mice., International Immunopharmacology, 17(2), 254-9, 2013, Elsevier(3.1180)

  26. Gopalakrishnan R, Sundaram J, Sattu K, Pandi A, Thiruvengadam D, Dietary supplementation of silymarin is associated with decreased cell proliferation, increased apoptosis, and activation of detoxification system in hepatocellular carcinoma., Molecular and Cellular Biochemistry, 377(1), 163-76, 2013, Springer Science+Business Media(2.0570)

  27. Anandakumar P,, Kamaraj S,, Jagan S, Ramakrishnan G, Asokkumar S, Naveenkumar C., The anticancer role of capsaicin in experimentallyinduced lung carcinogenesis, , 18(2), 19-25, 2015, Korean Pharmacopuncture Institute(1.0000)

  28. M Govindammal,, M Prasath, S Kamaraj, B Sathya, Invivo, molecular docking, spectroscopy studies of (S)-2, 3-dihydro-5, 7-dihydroxy-2 (3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one: a potential uptake PI3/AKT inhibitor, Biocatalysis and Agricultural Biotechnology, 18(2019), 101086-101098, 2019, Elsevier(2.4000)

  29. Sattu Kamaraj,, Pandi Anandakumar, Sundaram Jagan, Gopalakrishnan Ramakrishnan, Prabu Periyasamy, Selvamani Asokkumar, Raghunandhakumar Subramanian, Thiruvengadam Devaki, Hesperidin inhibits cell proliferation and induces mitochondrial-mediated apoptosis in human lung cancer cells through down regulation of β-catenin/c-myc, Biocatalysis and Agricultural Biotechnology, 18(2019), 101065-101072, 2019, Elsevier(2.4000)

  30. Sathishkumar Vinayagam, Kamaraj Sattu, SARS-CoV-2 and coagulation disorders in different organs, Life Sciences , 260(2020), 118431-118441, 2020, Elsevier(3.6400)

  31. K Ramamoorthy, Subramanian Raghunandhakumar, RS Anand, A Paramasivam, S Kamaraj*, S Nagaraj, Devaraj Ezhilarasan, Thangavelu Lakshmi, Kamal Dua, Dinesh Kumar Chellappan, Ashokkumar Veeramuthu, Anticancer effects and lysosomal acidification in A549 cells by Astaxanthin from Haematococcus lacustris , Bioinformation , 16(11), 965-973, 2020, Biomedical Informatics

  32. A Vidyasakar, S Krishnakumar, K Suresh Kumar, K Neelavannan, S Anbalagan, K Kasilingam, S Srinivasalu, P Saravanan, S Kamaraj, NS Magesh, Microplastic contamination in edible sea salt from the largest salt-producing states of India, Marine Pollution Bulletin, 171(2021), 112728-112728, 2021, Elsevier(5.5500)

  33. Anandakumar P,, Kamaraj S,, Vanitha MK., D‐limonene: A multifunctional compound with potent therapeutic effects, Journal of Food Biochemistry, 45(1), 13566-13575, 2021, Wiley-Blackwell(1.6600)

  34. Govindammal M,, Prasath M,, Kamaraj S, Muthu S, Selvapandiyan M, Exploring the molecular structure, vibrational spectroscopic, quantum chemical calculation and molecular docking studies of curcumin: A potential PI3K/AKT uptake inhibitor, Heliyon, 7(4), 6646-6660, 2021, cell press